Have you heard the theory that Barry is Superman? He wears a blue suit with a touch of red (the tie), he has super-strength (breaks the "indestructible" handle), he "flies" when he leaps over that one barrier, etc. I think there's other stuff, but it kinda works in a weird way, at least with some aesthetic flourishes like that.
As for diagnosing him clinically/psychologically, well, for starters, I'm not sure "externally-induced" follows the same rules. These are neuroses, suitable for Freudian analysis, not necessarily a brain-chemistry thing that a medical doctor (psychiatrist...I think...?) would treat.
Symptoms of mania can include things like latching on to get-rich quick schemes, making bad money decisions, acting impulsively, and displaying emotional range like anger or elation. We do see him freak out over the coupon thing, dancing in the store, violently lashing out several times, and engaging in phone sex (including just flinging his credit card number everywhere). That's kinda manic.
I could see autistic, too, but he'd be HIGH functioning, because of the way he interacts and relates with people.
Generally, I'd agree with manic, but maybe throw in some "borderline personality disorder" (if I'm remembering it correctly...), and I'd attribute a lot, most, or all of it coming from his sisters' (mis)treatment of him. His family life is clearly causing a lot of this.
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