Two things:
1. Yes, there are many people who can imitate Hoffman's character and thus play him. But Hoffman came up with this character himself. He studied a guy with autism, he worked on all the mannerisms, he perfected it. It wasn't just a caricature, either. There were little nuances that you can pick up on. Like a little look in his eyes towards the end of the movie when he looks at his brother that says a little something extra.
2. Yes, Cruise had the more difficult job in this movie, because he was the one holding the movie up, and his character had an arc. Cruise in his heyday was always highly underrated as an actor because of his looks (yet somehow whenever he was in a movie, everyone had to go watch it, which you can only say for maybe a handful of actors in history, most of them from old Hollywood), but just for a moment imagine if someone like Shia LaBeauf (however you spell it) was the lead in this movie, assuming he was acting in the 80's. Do you think the movie would be as highly acclaimed? Would anyone remember it? I seriously doubt it.
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