Is there any downside for Pence if he removes Trump?
In the short term of course the hardcore Trump fans will be mad at him. But if Pence removes Trump that would make him the 46th President of the United States. He would go down in history as one of the presidents. As a former president he would get lifetime secret service protection. Also, the fact that he would have such a short tenure as president would make him a curiosity for future generations. This could potentially make him more well known than many other former presidents.
Other than short term anger from Trump fans (who already don't like Pence because he certified the votes) is there any downside for him in using the 25th amendment to remove Trump?