I think if any enemy is going to be teaming up with The Hand, its likely going to be Madame Gow. She's stated that she had other intentions in NY beyond just selling heroin. It's also been noted that Season 1 of Iron Fist will deal with Danny seeking vengeance on the man who killed his parents and tried to kill him. It's possible he may have some connection to Madame Gow and Gow will likely appear in Iron Fist (as she's an Iron Fist villain), she could become one of the main antagonist of the first season, but with the way she was set up in Daredevil, I think whatever she's up to is going to be tied to The Hand. Either that or she'll join forces with The Hand to keep Danny from interfering in her plans as Danny is a legitimate threat to her.
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