My predictions for who dies (NOT SPOILERS, just THEORIES)
Iron Man: Robert Downey Jr. is the highest paid actor in the world currently, and his contract is ending. it would make sense financially to kill him off.
Captain America: Same. Contract expiring, setting up Bucky or Falcon to take up the mantle.
Gamora: Disney can use the X-Men now, and Star-Lord ends up with Kitty Pryde in the comics, so it would make sense for her to die, since she's now a third wheel. And if she doesn't die in this one, she'll die for sure in GOTG 3.
Nebula: It would make sense for Thanos to kill both his children.
Vision: He has the Mind Stone.
Hulk: Because of rights issues with Universal, and also to show how powerful Thanos truly is. If he can kill Hulk, he can kill anyone!
Post-credits scene theory: Doctor Strange dies and opens a portal to another dimension to go to Charles Xavier's School for the Incredibly Gifted.
Dr Strange: Hello. Prof. X. My name is Dr. Stephen Strange. May I borrow a few of your students?
(Wolverine comes back to life because Deadpool resets the timeline in Deadpool 2. (Not a spoiler for Deadpool 2, btw. Just a theory)
Wolvie: 'Sup bub.
(That or Dr. Strange recruits the Fantastic Four)
Also, Agents of SHIELD make a cameo now that Skye is Quake and it would shock the Avengers to see Coulson alive