predict Scream 8
Yeah, you read right. And why not, because who are we kidding. It's like all other horror franchises. Even if they try to end it, another way to resurrect it will always be in the pipeline.
Honestly, I think in regards to Sam and Tara. They could explain them away like Sidney in 6. They've gone into hiding. Short and simple and sweet. The writers know that the less they say now, the less they'll be painted into a corner later. So they can do 7 without them. And then in a few years maybe, the studio and Melissa Barrera can come to peace, and Jenna Ortega can find the time, and we catch up with those characters down the road. Just like we presumably/hopefully will with Sidney in 7.