How about a METH HEAD zombie film?
We've had numerous zombie films. We just had radiated mutant psychos who act like zombies. What about a meth clinic who mistakenly releases all their meth addicts onto the streets of an abandobed Detroit-esque ghetto and a wayward group of people run into them?
Hardcore drug users are scary. Look at meth users pics on Google. The before/after pictures are pretty unsettling. Plus, they tear at their own faces and skin, thinking bugs are crawling underneath. Imagine ten of them coming at you.
Now all we need is a well-written plot with true GOOD acting to make it stick. CD unfortunately didn't do it, save for the scary environment.
What do you all think? Psycho meth addicts. Sounds good to me.