This movie, even more so then the first, is set in a world of environmental and urban decay. Everyone in the first movie were pretty rough looking, but Ryan Gosling looks like he's holding up pretty well for a street cop.
Well in the first movie I kind of felt like the upper class people were pretty clean cut, tyrell, rachel and tyrell corporation staff in general looked pretty neat and orderly. There are shaved and not too rugged regular cops seen in Blade Runner as well. You just gotta look real close to notice these things because there is often a lot going on screen in Blade Runner. But Gosling definitely by nature doesn't look as rugged as harrison, he doesn't have the deep lines in his face. I still think he will do well, and if Goslings character ends up being a replicant...well theres another possible reason.