'look at what they make you give.'

[deleted]

I've always thought they were referring to identity and/or humanity. Jason had just asked him "Do you even know why you're supposed to kill me?" People like Jason and The Professor have been stripped of their identities and their humanity, and turned into killing machines. They're not supposed to think or reason for themselves. They're just told to kill someone and they do it.

Please don't feed the trolls.

It's tied into the same experience Bourne's just had. Think about the scene pretty much just prior, when Bourne is flashing back to his training. The program "assets" are trained in a way that they're willing to execute people when it's just an anonymous person whose head is in a bag, no questions asked. The Professor, Paz, Bourne, they've all had the same training, so they've all fundamentally had free will and the ability to ask questions stripped away. Or, more accurately, they've given those things away. Individuality, any free will, and even the ability to question what's going on - that's what "they make you give."

Presumably, all of them original gave these things up to someone they thought they could trust, but all of the assets have been used in ways that don't help anyone but the handler. The constant chase of Bourne in all three movies is basically based on the idea that he MIGHT be a threat. Or might BECOME a threat in some potential future. And for that, he's to be executed... by other assets who don't even get to know that Bourne is just one of them who wants out.

Clearly, The Professor had started to question this in "The Bourne Identity", but not in time to save his own life, but Bourne is basically passing on the thought to Paz.