Well, something in the body can break if you abuse the body, so that it will have an overly adverse effect to some substance, even if the body mostly functions otherwise well. It's like sensitizing your body to react a certain way to some substance.
I read this story of a guy who drank so much coffee that the doctor told him he has to go cold turkey immediately or probably die, and he suffered powerful withdrawal effects that almost did probably kill him, and now if he drinks coffee again, it would be very dangerous to him.
I don't know how much of this story is true, if any, but I don't see why it couldn't happen. Strange things happen.. body can't always heal itself to 100% after an abusive era. Sometimes malfunctions remain, but you are OK if you don't abuse your body again.
Of course, in the end, every single body will lose its capability of sustaining a soul, so then you return to where you came from, but that's another story for another day.
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