I'd say the only real reason why hitmen (might) and certain military personnel do use the .22l.r. is because it is hands down the best common cartridge there is if maximum suppression of the muzzle signature is your goal. (The Israelis have or had suppressed Ruger 10/22 rifles to take out cameras, lights and guard dogs and apparently certain US Spec Ops also had integrally suppressed Rugers for certain applications)
There may be a few additional benefits, but they aren't the reason why the caliber is used. If it were, then the .22l.r. would also be used without a suppressor by military personnel.
Although I would be no less cautious standing in front of the muzzle of a .22 than I would in front of a .45 there is no arguing that it is definitely not the most suitable caliber option for concealed carry self defence.
a) A .22l.r. is absolutely lethal. But odds are, forgive my morbid example, if you randomly (random = not well aimed = under stress = moving targets) shot 10 people with a .22 pistol and 10 more with a 9mm/ .40s&w/ .45acp or whatever, that you will have inflicted more damage on the people hit with the larger caliber weapons. So if you wish to play it safe, you're better off not opting for a .22l.r. for self defence - even if you (think) you are a good shot.
b) Another major reason why I'd consider the .22l.r. inferior is because it is (in my experience) more prone to jamming and malfunctioning. Twenty-twos can be picky with their ammo, so finding the right brand etc. will greatly eliminate this issue. Still, if a 9mm fails to go back into battery after firing a shot, you can slap the back of the slide forward and the problem will most likely be solved. Do this with your Ruger MK series .22 pistol and you will most likely squash the case or deform the projectile to the extent that it won't chamber anymore. This is where it gets really exiting if people are shooting back at you (sarcasm).
Knock down power or better "stopping power" as stated above by someone else does NOT actually mean the bullet's ability to knock you off your feet, but rather its ability to incapacitate you (even without hitting you in the head or other vital organs). Everyone has his own favourite calibers, so I won't get started on 9mm vs. .45ACP etc. besides, the self defence ammo available these days makes the 9mm a whole lot more effective than it once was.
People may argue:
- the .22s ping pong effect in the brain is a pro.
while this may or may not be true (i've never met a pathologist with first hand experience) there is no way that you'll feel any less dead if a hollow point 9mm went through your skull and emptied it on its way out the back.
- the .22 is more likely to deform to the extent that forensics can't identify the rifling on the bullet and match it to other crimes.
True, but to rely on this on every hit would be a little optimistic.
- the .22 has less of a risk of over penetration.
True, but hollow points etc. minimise this risk on all ammo and i'm fairly certain that law enforcement is more concerned with this issue than hitmen, yet they still use larger calibers.
- a .22 is also less likely to go through an object a target is taking cover behind (like Julian Moore's kitchen in this movie) or even through your clothes if you're wearing a thick winter jacket and have a wallet with lots of coins etc. in it and the bullet just so happened to hit that... it's tacky but true... and yes, in Europe people actually do tend to have coins since most places don't have 1 dollar bills etc.
All in all the only reason why the .22l.r. may or may not be used by hitmen is because it is the quietest caliber there is when suppressed (probably even unsuppressed or if you're going to improvise and use a pillow or something). Also, it's readily available!
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