What about Pearl?!
When Tobey and his mum run off at then end of the film, they leave poor Pearl all alone with the monstrous Dwight! I know that at the end of the film it says she went on to do all right in Seattle, but don't you think it was verging on neglect to leave without her? Throughout the film the mum and her appeared to be close (holding hands, playing that jigsaw puzzle and so on), so the whole thing strikes me as odd.
Does it say anything in the book about what happens to her before she leaves home? It really bugged me...